Scherner, Cathrin published the artcileA novel route to 6-substituted piperidin-3-ols via domino cyclization of 2-hydroxy-6-phosphinyl-5-hexenyl tosylates with primary amines: synthesis of (¡À)-pseudoconhydrine and (¡À)-epi-pseudoconhydrine, Recommanded Product: Allyldiphenylphosphine oxide, the publication is Synthesis (2014), 46(18), 2506-2514, database is CAplus.
2-Hydroxy-6-phosphinyl-5-hexenyl tosylates, oxirane ring-opening products derived from glycidyl tosylates and phosphinyl- substituted allyl anions, undergo domino SN2-Michael reactions with primary amines to give 6-phosphinylmethyl piperidin-3-ols. The phosphinyl unit can be used in Horner olefination reactions. This approach is applied to the synthesis of racemic pseudoconhydrine (I) and its epimer II.
Synthesis published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C15H15OP, Recommanded Product: Allyldiphenylphosphine oxide.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia