Chen, Chaohuang published the artcilePalladium(II)-Catalyzed Aminotrifluoromethoxylation of Alkenes: Mechanistic Insight into the Effect of N-Protecting Groups, Application of 2,2-Diallylpent-4-en-1-amine, the publication is Chinese Journal of Chemistry (2020), 38(4), 346-350, database is CAplus.
An efficient palladium-catalyzed regioselective 5-exo aminotrifluoromethoxylation of alkenes was established herein, which provided a practical route toward the synthesis of OCF3-containing pyrrolidines such as I [R1 = H, allyl, 4-ClC6H4, etc.; R2 = allyl, Bn, 4-FC6H4, etc.; R1R2 = (CH2)3, (CH2)4, (CH2)2O(CH2)2, etc.] and II. Tert-Butyloxycarbonyl (Boc) as an amino protecting group played a significant role in both chemo- and regioselectivities. In addition, preliminary mechanistic studies revealed that amino protecting group of substrates and counter anion of palladium catalyst play critical roles in reaction efficiency presumably due to an isomerization of alkyl- Pd(II) intermediates. Moreover, the asym. 5-exo aminotrifluoromethoxylation reaction had also been achieved by introducing a sterically bulky pyridinyl-oxazoline ligand.
Chinese Journal of Chemistry published new progress about 928836-00-4. 928836-00-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Amine,Aliphatic hydrocarbon chain, name is 2,2-Diallylpent-4-en-1-amine, and the molecular formula is C11H19N, Application of 2,2-Diallylpent-4-en-1-amine.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia