Du, Manfei published the artcileRegiospecific amino bromine addition of ¦Â-nitrostyrene derivatives with acrylamide and N-bromobutanimide, Related Products of catalysis-chemistry, the publication is Gaodeng Xuexiao Huaxue Xuebao (2016), 37(5), 902-911, database is CAplus.
A new protocol for the high regioselective aminobromination of ¦Â-nitrostyrene derivatives with acrylamide and N-Bromobutanimide (NBS) as nitrogen/bromine sources was developed. ¦Â-Nitrostyrene derivatives reacted with acrylamide and NBS promoted by CH3CH2ONa at room temperature (without the protection of an inert gaseous atm.) in CH2Cl2, offered vicinal haloamine products in good yields (up to 83%). For the ¦Â-methyl-¦Â-nitrostyrene, the good yields (up to 98%) were also achieved in CH3OH promoted by Na2CO3. Although the strong electron-donating substituents (e.g., OCH3) on the 4-position of benzene ring could deactivated the reaction activity of ¦Â-nitrostyrene derivatives, the vicinal haloamines were also afforded as the sole addition product. Whereas strong electron-withdrawing substituents (e.g., NO2) could activated reaction activity remarkably and the vicinal haloamines were afforded as the sole addition product, too. The result revealed that the addition reaction had a nucleophilic addition feature. The aminobromination of 25 examples of ¦Â-nitrostyrenes were investigated and the structure of all products were confirmed by the corresponding NMR (NMR) spectra and high resolution mass spectrometer (HRMS). A possible mechanism involving a nucleophilic conjugate addition was proposed.
Gaodeng Xuexiao Huaxue Xuebao published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H11NO4, Related Products of catalysis-chemistry.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia