Eggleston, Drake S. published the artcileTetrasubstituted [14]-1,3,8,10-tetraeneN4 macrocyclic complexes: synthesis, organic precursor, and template reaction mechanism, Computed Properties of 10517-44-9, the publication is Inorganic Chemistry (1980), 19(6), 1593-9, database is CAplus.
Template syntheses have been studied for macrocyclic complexes derived from 1,3-diaminopropane (DAP), 1-phenyl-1,2-propanedione (AB), and metal(II) acetate, where the metal is Fe, Co or Ni. The products were characterized by elemental analyses and conductivity and spectroscopic methods (IR, UV-visible, and 1H and 13C NMR). The 13C NMR anal. indicated that the template synthesis is regiospecific, producing only one of the two possible isomeric products corresponding to the ligand 2,9-dimethyl-3,10-diphenyl-1,4,8,11-tetraazacyclotetradeca-1,3,8,10-tetraene, trans-MePhTIM. X-ray diffraction data for a crystal of [Co(MePhTIM)Cl2]PF6 are also consistent with a centrosym. trans isomer product. 1H NMR studies of the 1:1 condensation of AB and DAP in the absence of metals indicates a mixture of products from which the major product was isolated and found to be 2-benzoyl-2-methylhexahydropyrimidine. Reaction of this compound with metal salts yields the isomerically pure trans-MePhTIM complexes. The synthetic results and 1H NMR studies are consistent with a proposed template mechanism in which AB and DAP react first to form 2-benzoyl-2-methylhexahydropyrimidine in equilibrium with its open-chain Schiff-base tautomer. Subsequent condensation of two of the Schiff-base mols. under the influence of a metal ion leads exclusively to the trans-MePhTIM complex. Results of other experiments and syntheses using an unsym. substituted alkyl ¦Á-diketone indicate that the mechanism is also applicable to related systems.
Inorganic Chemistry published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, Computed Properties of 10517-44-9.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia