Lee, Kang-sang published the artcileMonodentate Non-C2-symmetric Chiral N-Heterocyclic Carbene Complexes for Enantioselective Synthesis. Cu-Catalyzed Conjugate Additions of Aryl- and Alkenylsilylfluorides to Cyclic Enones, Recommanded Product: Difluorodiphenylsilane, the publication is Journal of Organic Chemistry (2009), 74(12), 4455-4462, database is CAplus and MEDLINE.
A new class of enantioselective conjugate addition (ECA) reactions that involve aryl- or alkenylsilyl fluoride reagents and are catalyzed by chiral non-C2-sym. Cu-based N-heterocyclic carbene (NHC) complexes are disclosed. Transformations were designed based on the principle that a catalytically active chiral NHC-Cu-aryl or NHC-Cu-alkenyl complex can be accessed from reaction of a Cu-halide precursor with in situ-generated aryl- or alkenyltetrafluorosilicate. Reactions proceed in the presence of 1.5 equiv of the aryl- or alkenylsilane reagents and 1.5 equiv of tris(dimethylamino)sulfonium difluorotrimethylsilicate (TASF). Desired products are isolated in 63-97% yield and 73.5:26.5-98.5:1.5 enantiomeric ratio (47%-97% ee). A major focus of the present studies is the design, evaluation, and development of new chiral imidazolinium salts and their derived NHC-Cu complexes as catalysts that promote reactions of various carbosilanes to a range of electrophilic substrates. Toward this end, nearly 20 new chiral monodentate imidazolinium salts, most of which are non-C2-sym., were prepared and fully characterized and their ability to serve as catalysts in the ECA reactions was studied.
Journal of Organic Chemistry published new progress about 312-40-3. 312-40-3 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Difluorodiphenylsilane, and the molecular formula is C12H10F2Si, Recommanded Product: Difluorodiphenylsilane.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia