Cho, Hong Je published the artcileSelective Synthesis of 4,4′-Dimethylbiphenyl from 2-Methylfuran, Synthetic Route of 613-33-2, the publication is ACS Sustainable Chemistry & Engineering (2021), 9(8), 3316-3323, database is CAplus.
4,4′-Dimethylbiphenyl (DMBP) is a promising platform chem. for the production of polymer precursors, plasticizers, and metal-organic frameworks among other materials. We report a two-step process to produce DMBP from 2-methylfuran (MF) via the formation of the intermediate 5,5′-dimethyl-2,2′-bifuran (DMBF). DMBF is generated from the Pd-catalyzed oxidative coupling of MF in the presence of trifluoroacetic acid (TFA) with high selectivity (94%). Optimization of reaction conditions yields a 20-fold increase in site-time-yield (STY = 6.99 h-1) compared with a previously reported protocol. High O2 pressure (7 bar) and a high TFA concentration (3 M) are critical to improve the DMBF formation rate. For the conversion of DMBF to DMBP, we show that phosphoric acid supported on silica (P-SiO2) catalyzes tandem Diels-Alder and dehydration reactions of DMBF with ethylene to produce DMBP (83% yield). The high yield and selectivity are a consequence of the weak Bronsted acid sites in P-SiO2 that dehydrate furan-ethylene cycloadducts without substantial formation of carbon deposits.
ACS Sustainable Chemistry & Engineering published new progress about 613-33-2. 613-33-2 belongs to catalysis-chemistry, auxiliary class Benzene, name is 4,4′-Dimethyldiphenyl, and the molecular formula is C14H14, Synthetic Route of 613-33-2.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia