Garcia, Joel published the artcilePhysical Properties of Eu2+-Containing Cryptates as Contrast Agents for Ultrahigh-Field Magnetic Resonance Imaging, Synthetic Route of 5411-14-3, the publication is European Journal of Inorganic Chemistry (2012), 2012(12), 2135-2140, database is CAplus and MEDLINE.
The kinetic stabilities and relaxivities of a series of Eu2+-containing cryptates have been investigated. Transmetallation studies, which monitored the change in the longitudinal relaxation rate of water protons in the presence of Ca2+, Mg2+, and Zn2+, demonstrated that the cryptate structure influenced the stability, and two of the cryptates studied were inert to transmetalation in the presence of these endogenous ions. The efficacy of these cryptates was determined at different magnetic field strengths, temperatures, and pH values. Cryptate relaxivity was found to be higher at ultrahigh field strengths (7 and 9.4 T) relative to clin. relevant field strengths (1.4 and 3 T), but the efficiency of these cryptates decreased as the temperature increased. In addition, a variation in pH did not yield significant changes in the efficacy of the cryptates. These studies establish a foundation of important properties that are necessary to develop effective pos. contrast agents for magnetic resonance imaging from Eu2+-containing cryptates.
European Journal of Inorganic Chemistry published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, Synthetic Route of 5411-14-3.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia