Hargreaves, John S. published the artcileThe degradation of dG phosphoramidites in solution, Category: catalysis-chemistry, the publication is Nucleosides, Nucleotides & Nucleic Acids (2015), 34(10), 691-707, database is CAplus and MEDLINE.
The reaction of 2′-deoxynucleoside phosphoramidites with water is an important degradation reaction that limits the lifetimes of reagents used for chem. deoxyoligonucleotide synthesis. The hydrolysis of nucleoside phosphoramidites in solution has therefore been investigated. The degree of degradation depends not only on the presence of water but also on the specific nucleoside, 2′-deoxyguanosine (dG) being especially susceptible. Addnl., the nature of the group protecting the exocyclic amine on the nucleoside base strongly influences the rate of hydrolysis. For dG, the degradation is 2nd-order in phosphoramidite concentration, indicating autocatalysis of the hydrolysis reaction. Comparison of the degradation rates of dG phosphoramidites with different protecting groups as well as with phosphoramidites containing bases that are structurally similar to dG afforded clues to the nature of how dG catalyzes its own destruction and indicated a direct correlation between ease of protecting group removal and the propensity to undergo autocatalytic degradation
Nucleosides, Nucleotides & Nucleic Acids published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, Category: catalysis-chemistry.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia