Hussein, Ahmad Q. published the artcileReactions of ¦Á-bromo isothiocyanates, Safety of 1,1-Dimethylthiourea, the publication is Chemische Berichte (1979), 112(6), 1956-72, database is CAplus.
The reactions of RR1CBrNCS [I; R = R1 = Me, RR1 = (CH2)5, R, R1 = Me2CH, CO2Me; Me3C, Ph; H, Ph; Me3C, Br] are described. I having ¦Â-H atoms (1st 3 compounds) eliminate HBr to form vinyl isothiocyanates, e.g., CH2:CMeNCS. H2O hydrolyzes I to carbonyl compounds RR1CO. Whereas hard nucleophiles substitute the Br in I, soft nucleophiles add to the C atom of the NCS group. The chem. properties of the products, including heterocycles and geminal diisothiocyanates, are examined Me2C:NC(S)NMe2 shows hindered rotation about the C(S)-N and C:N bonds.
Chemische Berichte published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Safety of 1,1-Dimethylthiourea.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia