Kang, Taek published the artcileIridium-Catalyzed Intermolecular Amidation of sp3 C-H Bonds: Late-Stage Functionalization of an Unactivated Methyl Group, HPLC of Formula: 6084-58-8, the publication is Journal of the American Chemical Society (2014), 136(11), 4141-4144, database is CAplus and MEDLINE.
Reported herein is the iridium-catalyzed direct amidation of unactivated sp3 C-H bonds. With sulfonyl and acyl azides as the amino source, the amidation occurs efficiently under mild conditions over a wide range of unactivated Me groups with high functional group tolerance. This procedure can be successfully applied for the direct introduction of an amino group into complex compounds and thus can serve as a powerful synthetic tool for late-stage C-H functionalization. Thus, e.g., [IrCp*Cl2]2/AgNTf2-catalyzed amidation of ketoxime I with TsN3 in 1,2-DCE in presence of catalytic AgOAc afforded sulfonamide II (90%).
Journal of the American Chemical Society published new progress about 6084-58-8. 6084-58-8 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is O-Isobutylhydroxylamine hydrochloride, and the molecular formula is C4H12ClNO, HPLC of Formula: 6084-58-8.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia