Pasha, Mohammed Anif published the artcileOrganocatalytic Reductive Propargylation: Scope and Applications, Category: catalysis-chemistry, the publication is Journal of Organic Chemistry (2019), 84(23), 15399-15416, database is CAplus and MEDLINE.
An amino acid-catalyzed three-component reductive coupling protocol has developed for the selective high-yielding synthesis of nearly fifty examples of propargylated cyclic/acyclic systems from the various propargyl aldehydes, cyclic/acyclic CH-acids, and Hantzsch ester at the ambient conditions. It is an economical, efficient, catalytic, metal-free protocol for the quick gram scale synthesis of propargylated cyclic/acyclic compounds and many of these coupling compounds were purified by simple precipitation-filtration technique instead of column chromatog. Functionally rich propargylated cyclic-1,3-diketones were specifically transformed into dihydropyrans found in natural products and drugs through an annulative etherification reaction by using Lewis-acid (AgOTf) catalysis. Further C-methylation reactions on propargylated cyclic-1,3-diketones, which are prolific synthons in natural products and medicinal chem are developed.
Journal of Organic Chemistry published new progress about 2051-95-8. 2051-95-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ketone, name is 3-Benzoylpropionicacid, and the molecular formula is C10H10O3, Category: catalysis-chemistry.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia