Cui, Wen published the artcileMitsunobu-reaction-based total solid-phase synthesis of Fanlizhicyclopeptide B, HPLC of Formula: 71989-31-6, the publication is Chemistry of Natural Compounds (2021), 57(6), 1086-1089, database is CAplus.
The first total synthesis of anti-inflammatory cyclic peptide fanlizhicyclopeptide B based on the Mitsunobu reaction is reported. The pre-made Fmoc-Tyr-OAllyl building block was coupled to the Wang resin via the Mitsunobu reaction catalyzed by triphenylphosphine and di-Et azodicarboxylate. After the remaining amino acids were assembled, macrocyclization was realized on solid support. Finally, the crude product was cleaved from resin and then purified by preparative reverse-phase high-performance liquid chromatog. (RP-HPLC) to provide the pure target fanlizhicyclopeptide B.
Chemistry of Natural Compounds published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, HPLC of Formula: 71989-31-6.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia