Fukui, Yuki published the artcileTunable Arylative Cyclization of 1,6-Enynes Triggered by Rhodium(III)-Catalyzed C-H Activation, Recommanded Product: O-Pivaloylhydroxylamine trifluoromethanesulfonate, the publication is Journal of the American Chemical Society (2014), 136(44), 15607-15614, database is CAplus and MEDLINE.
Two tunable arylative cyclizations of cyclohexadienone-containing 1,6-enynes, e.g., I, are reported via rhodium(III)-catalyzed C-H activation of O-substituted N-hydroxybenzamides. The use of different O substituents, i.e., O-Piv and O-Me, on the directing group allows the formation of either tetracyclic isoquinolones, e.g., II, through an N-Michael addition process or hydrobenzofurans, e.g., III, through a C-Michael addition process. Mechanistic investigations of these two cascade reactions clearly indicated that the C-H bond cleavage process was involved in the turnover-limiting step. Furthermore, the cyclization products could be subjected to various transformations for elaborating the pharmaceutically and synthetically valuable potential. This is the first example of a rhodium(III)-catalyzed arylative cyclization reaction of 1,6-enynes, and the results extend the application realm of Cp*RhIII-catalyzed C-H activation cascade reactions.
Journal of the American Chemical Society published new progress about 1293990-73-4. 1293990-73-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is O-Pivaloylhydroxylamine trifluoromethanesulfonate, and the molecular formula is C6H12F3NO5S, Recommanded Product: O-Pivaloylhydroxylamine trifluoromethanesulfonate.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia