Latosinska, J. N. published the artcileNature of Isomerism of Solid Isothiourea Salts, Inhibitors of Nitric Oxide Synthases, As Studied by 1H-14N Nuclear Quadrupole Double Resonance, X-ray, and Density Functional Theory/Quantum Theory of Atoms in Molecules, Name: 1,1-Dimethylthiourea, the publication is Journal of Physical Chemistry A (2012), 116(5), 1445-1463, database is CAplus and MEDLINE.
Isothioureas, inhibitors of nitric oxide synthases, have been studied exptl. in solid state by nuclear quadrupole double resonance (NQDR) and X-ray methods and theor. by the quantum theory of atoms in mols./d. functional theory. Resonance frequencies on 14N have been detected and assigned to particular nitrogen sites in each mol. The crystal packings of (S)-3,4-dichlorobenzyl-N-methylisothiouronium chloride with the disordered chlorine positions in benzene ring and (S)-butyloisothiouronium bromide have been resolved in X-ray diffraction studies. 14N NQDR spectra have been found good indicators of isomer type and strength of intra- or intermol. N-H¡¤¡¤¡¤X (X = Cl, Br) interactions. From among all salts studied, only for (S)-2,3,4,5,6-pentabromobenzylisothiouronium chloride are both nitrogen sites equivalent, which has been explained by the slow exchange. This unique structural feature can be a key factor in the high biol. activity of (S)-2,3,4,5,6-pentabromobenzylisothiouronium salts.
Journal of Physical Chemistry A published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Name: 1,1-Dimethylthiourea.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia