Wang, Bo published the artcileSyntheses and structure-activity relationship studies of N-substituted-¦Â-D-glucosaminides as selective cytotoxic agents, Application In Synthesis of 16909-09-4, the publication is Bioorganic & Medicinal Chemistry Letters (2012), 22(23), 7110-7113, database is CAplus and MEDLINE.
Twenty-four diosgenyl saponins bearing cinnamoyl, carbamido and thiosemicarbazone groups, e.g. I (R = H, R1 = Me, OMe; R = OMe, R1 = H), were synthesized concisely. The cytotoxicities of the synthetic compounds on six human caner cell lines were evaluated employing MTT method. Structure-activity relationship could be observed, and two of the synthesized compounds I (R = H, R1 = Me, OMe) exhibited selective inhibition on HeLa and MCF-7 cells, while three of them, e.g. I (R = OMe, R1 = H), showed strong inhibition against HT1080.
Bioorganic & Medicinal Chemistry Letters published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C7H10O4, Application In Synthesis of 16909-09-4.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia