Wang, Mei published the artcileBiomimetic synthesis and anti-inflammatory effects of horsfiequinone A, Related Products of catalysis-chemistry, the publication is Tetrahedron Letters (2021), 152756, database is CAplus.
Inspired by the oxy-tyrosinase type II copper enzyme, a biomimetic synthesis of the natural product horsfiequinone A (I) has been achieved using CuOTf/DBED/O2 catalyzed oxidation as a key step. The synthetic route furnished 1 in 33% overall yield (64% brsm) from com. available para-hydroxybenzaldehyde. Moreover, revisiting the biol. activity of 1 resulted in the discovery of its in vitro inhibitory activity towards nitric oxide (NO) production in LPS-induced RAW264.7 cells with an IC50 value of 4.42 ¡À 0.81¦ÌM. The anti-inflammatory effect of 1 was further supported by an iNOS expression inhibition assay and mol. docking simulation.
Tetrahedron Letters published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C6H9N3, Related Products of catalysis-chemistry.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia