Zoh, Dyung Duk published the artcileCooperation of ¦Â-cyclodextrin with macrocyclic metal centers in the action of artificial metalloesterases built on poly(ethylenimine), Computed Properties of 1798-04-5, the publication is Bioorganic Chemistry (1994), 22(3), 242-52, database is CAplus.
¦Â-Cyclodextrin (CD) was attached to poly(ethylenimine) (PEI), and then macrocyclic metal centers were constructed on the polymer by condensation with glyoxal or butanedione in the presence of metal (ZnII, NiII, or CoII) templates. The resulting polymers were treated with acetic anhydride to block primary or secondary amines. Hydrolysis of 2 nitrophenyl esters containing t-butylphenyl residues in the acyl moieties was catalyzed by the PEI derivatives containing both CD cavities and macrocyclic metal centers. Anal. of the kinetic data indicated that the CD cavities and the metal centers provided binding sites and catalytic sites, resp., for the ester substrates, mimicking metalloesterases. Although the content of the metal center was much smaller for the ZnII-containing artificial enzyme compared with the NiII and CoII analogs, catalytic efficiency was greater for the ZnII derivative Kinetic data indicate high reactivity of the metal center in the productive complex formed between the catalyst and the substrate, when the unproductive binding by the CD cavities is considered.
Bioorganic Chemistry published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C5H10N2OS, Computed Properties of 1798-04-5.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia