Corradi, Silvia published the artcileSynthesis of Bromoundecyl Resorc[4]arenes and Applications of the Cone Stereoisomer as Selector for Liquid Chromatography, Recommanded Product: (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, the publication is Journal of Organic Chemistry (2018), 83(15), 7683-7693, database is CAplus and MEDLINE.
As an extension of the authors’ studies on the multifaceted properties of C-alkylated resorc[4]arenes, the authors planned to immobilize on a solid support resorc[4]arenes with C11-long side chains in the lower rim. To this purpose, the authors synthesized two conformationally diverse resorc[4]arenes containing a bromoundecyl moiety in the four axial pendants. The cone stereoisomer 6a (30% yield) was selected for the reaction with an aminopropylated silica gel (APSG) obtained from spherical Kromasil Si 100, 5 ¦Ìm particles, to give the corresponding immobilized SP-C11-resorc[4]arene system. The resulting polar-embedded stationary phase was fully characterized and studied in the HPLC discrimination of the E/Z stereoisomers of naturally occurring and semisynthetic combretastatins, a family of (Z)-stilbene anticancer drugs. The chair stereoisomer 6b (20% yield), when submitted to x-ray diffraction anal., showed a noteworthy self-assembly in the crystal lattice, with intercalated hydrophobic and polar layers as a result of intermol. Br¡¤¡¤¡¤O halogen bond interactions, according to a unique stacking motif. The potential and versatility of the SP-C11-resorc[4]arene stationary phase were shown as well in the separation of highly polar natural products (namely, flavonoids), under reversed-phase (RP) conditions, and of fullerenes C60 and C70, by using apolar solvents as mobile phases.
Journal of Organic Chemistry published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C11H12O4, Recommanded Product: (E)-3-(2,4-Dimethoxyphenyl)acrylic acid.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia