Cousse, Henri published the artcileSynthesis, structure and hypocholesteremic activity of a series of substituted ¦Ã-aryl-¦Ã-oxobutyric acids, Safety of 2-Methylene-4-oxo-4-phenylbutanoic acid, the publication is European Journal of Medicinal Chemistry (1987), 22(1), 45-57, database is CAplus.
4-Biphenylyl-2(or 3-)-methylene-4-oxobutyric acids, their isomers and derivatives, and some related compounds were prepared and tested for hypocholesteremic activity. Thus, reaction of 2-chlorobiphenyl with itaconic anhydride gave 4-(2-ClC6H4)C6H4COCH2C(:CH2)CO2H (I). The 2-Cl group in I resulted in high hypocholesteremic activity. Also prepared by standard methods were 4-biphenylyl-4-oxo-2-methyl-2-butenoic acids, hydroxybutenolides, and their acid chloride and amide derivatives
European Journal of Medicinal Chemistry published new progress about 15732-75-9. 15732-75-9 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ketone, name is 2-Methylene-4-oxo-4-phenylbutanoic acid, and the molecular formula is C11H10O3, Safety of 2-Methylene-4-oxo-4-phenylbutanoic acid.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia