Levene, P. A.’s team published research in Journal of Biological Chemistry in 110 | CAS: 1949-41-3

Journal of Biological Chemistry published new progress about 1949-41-3. 1949-41-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene, name is 2-Methyl-4-phenylbutanoic acid, and the molecular formula is C11H14O2, HPLC of Formula: 1949-41-3.

Levene, P. A. published the artcileConfigurational relationships of acids of the phenethyl series to those of the normal series, HPLC of Formula: 1949-41-3, the publication is Journal of Biological Chemistry (1935), 311-21, database is CAplus.

Substances of the type Ph(CH2)m.CHMe(CH2)nCO2H offer an opportunity to study the effect of the distance of the CO2H group from the asym. center when the distance of the Ph group is kept constant or varied. d-Ph(CH2)2CHMeCO2H has been configurationally correlated with l-Ph(CH2)2CHMeEt. Configurationally related 2-octyl- and 2-phenethylpropionic acids rotate polarized light in the same direction and, when m is 2, substitution of a hexyl by a Ph group does not change the direction of rotation of the EtCO2H substituted in position 2. In the phenethyl series change from n = 0 to n = 1 brings about the same change in the direction of rotation as in the octyl series. Exhaustive hydrogenation of the phenethyl group has no effect on the direction of rotation except in the case of Ph(CH2)2CHMe(CH2)2Br in which the direction is reversed in the hexahydro derivative The following compounds were prepared by methods given in the preceding abstract All rotations are for the homogeneous substances. l-Ph(CH2)2CHMeCO2H, b2 155¡ã, d432 1.042, [M]D32 -48.3¡ã, by CH2(CO2Et)2 synthesis and resolved by the cinchonidine salt; d-Et ester, b2 120¡ã, d428 0.979, [M]D28 7.6¡ã; l-Ph(CH2)2CHMeCH2OH, b17, 157¡ã, d428 0.968, [M]D28 -2.7¡ã; l-Ph(CH2)2CHMeCH2Br, b17 151¡ã, d427 1.235, [M]D27 -5.8¡ã; l-Ph(CH2)2CHMeCH2CO2H, b2 162¡ã, d427, 1.033, [M]D27 -6.04¡ã; l-Et ester, b2 131¡ã, d427 0.973, [M]D27 -4.9¡ã; l-Ph(CH2)2CHMe(CH2)2OH, b17, 157¡ã, d427 0.959, [M]D27; -3.99¡ã; l-Ph(CH2)2CHMe(CH2)2Br, b17 160¡ã, d427 1.201, [M]D27 -2.29¡ã; l-Ph(CH2)2CHMeEt, b15 112¡ã, d425 0.855, [M]D27 -4.76¡ã; d-C6H11CH2)2CHMeCO2H, b2 156¡ã, d427 0.968, [M]D27 3.4¡ã; d-Et ester, b1 101¡ã d428 0.919, [M]D28 4.92¡ã; l-C6H11(CH2)2CHMeCH2OH, b17 141¡ã, d427 0.898, [M]D27 -2.09¡ã; C6H11(CH2)2CHMeCH2Br, b15 142¡ã, [M] 0¡ã. l-C6H11(CH2)2CHMeCH2CO2H, b2 158¡ã, d427 0.959, [M]D27 -2.36¡ã; l-Et ester, b17 162¡ã, d425 0.918, [M]D25 -1.85¡ã; l-C6H11(CH2)2CHMe(CH2)2OH, b17 157¡ã, d427 0.893, [M]427 -1.84¡ã; d-C6H11(CH2)2 CHMe(CH2)2Br, b15 151¡ã, d427 1.122, [M]427 1.12¡ã; l-C6H11(CH2)2CHMeEt, b15 110¡ã, d427 0.806, [M]D27 -2.82¡ã.

Journal of Biological Chemistry published new progress about 1949-41-3. 1949-41-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene, name is 2-Methyl-4-phenylbutanoic acid, and the molecular formula is C11H14O2, HPLC of Formula: 1949-41-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia