Smith, Gerry A. published the artcileDesign of an indicator of intracellular free sodium concentration using fluorine-19 NMR, Category: catalysis-chemistry, the publication is Biochimica et Biophysica Acta, Molecular Cell Research (1986), 889(1), 72-83, database is CAplus and MEDLINE.
The development is described of a Na chelator with appropriate properties for an indicator of intracellular free Na concentration ([Na]i). The new indicator, FCryp-1 (I), is a tribenzo derivative of the parent (2:2:1) cryptand structure, incorporating the same F-substituted dibenzo 19F-NMR reporter group as the free [Ca2+] indicator, 5FBAPTA. I has appropriate affinity for Na+ (KNa = 101.3 M-1) and selectivity over other intracellular cations (KK; KCa; KMg < 10-1 M-1) for a [Na]i indicator. There is a 19F-NMR chem. shift of 2.00 ppm between free I and the Na-I complex, which provides a direct read out of free [Na]. I carries 4 carboxylate groups to confer aqueous solubility, which can be esterified with acetoxymethyl groups to render the indicator membrane permeant. Experiments on pig lymphocytes loaded with I gave an indicated [Na]i of 13.8 mM. The I structure can also be readily modified to provide fluorescent [Na]i indicators.
Biochimica et Biophysica Acta, Molecular Cell Research published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C7H8O3, Category: catalysis-chemistry.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia