Bregier-Jarzebowska, R. published the artcileInteractions of diamines with adenosine-5′-triphosphate (ATP) in the systems including copper(II) ions, Recommanded Product: Propane-1,3-diamine dihydrochloride, the publication is Journal of Inorganic Biochemistry (2016), 73-82, database is CAplus and MEDLINE.
Interactions were studied in the systems ATP/tn and ATP/Put (tn = 1,3-diaminopropane, Put = putrescine) whereas the complexation reactions in ternary systems Cu(II)/ATP/tn and Cu(II)/ATP/Put. Results of the potentiometric and spectroscopic studies evidenced the formation of adducts of the type (ATP)Hx(PA), where PA = diamine. The thermodn. stability of the complexes and the mode of interactions were determined The interaction products are (ATP)H3(tn) (1), (ATP)H2(tn) (2), (ATP)H3(Put) (3), and (ATP)H2(Put) (4). On the basis of anal. of changes in the positions of NMR signals, in the pH range of (ATP)H3(Put) (3) formation, the preferred centers of the interaction between ATP and Put are the endocyclic nitrogen atoms from the nucleotide. However, the shorter diamine tn in the entire pH range reacts with the phosphate groups from ATP. The pos. centers of noncovalent interactions are the protonated -NH+x groups from amines. In both complexes Cu(ATP)H2(tn) (9) and Cu(ATP)H3(Put) (11) formed in ternary systems at pH < 6.5, the amines are in the outer sphere of coordination with the noncovalent interaction with anchoring Cu(ATP). Only the phosphate groups from the nucleotide take part in metalation. At higher pH in the range of Cu(ATP)(PA) complex formation, significant differences in the reactions of the two amines appear. The shorter one (tn) binds Cu(II) ions with two nitrogen atoms, while putrescine coordinates in the monofunctional mode, which is undoubtedly related to the differences in lengths of methylene chain. This explains the considerable differences in the stability of Cu(ATP)(tn) (10) and Cu(ATP)(Put) (12). In both complexes the nucleotide is coordinated through phosphate groups. As a result of noncovalent interactions ATP forms mol. complexes with 1,3-diaminopropane and 1,4-diaminobutane (putrescine). Significant differences in the mode of interactions between the two diamines were observed in ATP/diamine binary systems and in ternary systems Cu(II)/ATP/diamine, at high pH.
Journal of Inorganic Biochemistry published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, Recommanded Product: Propane-1,3-diamine dihydrochloride.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia