Che, Zhiping published the artcileSynthesis of paeonol ester derivatives and their insecticidal, nematicidal, and anti-oomycete activities, HPLC of Formula: 118-90-1, the publication is Pest Management Science (2022), 78(8), 3442-3455, database is CAplus and MEDLINE.
Paeonol is extracted and isolated as a rich and sustainable natural bioresource from the root bark of Paeonia suffruticosa, the derivatives of which exhibit numerous biol. activities. It is well known that ester compounds play a very important role in pest control, such as organophosphorus, carbamate and pyrethroid pesticides. To discover biorational natural product-based pesticides, three series of (60) paeonol ester derivatives (7a-t, 8g,p, 9g,p, 10g-j,n-u, 11g,u, 12g,u, 13a-p, 14b,c, and 15b,c) were prepared by structural modification of paeonol, and their structures were well characterized by proton NMR (1H-NMR), carbon-13 NMR (13C-NMR), high-resolution mass spectrometry (HRMS), and m.p. Furthermore, we assessed the compounds as insecticidal, nematicidal, and anti-oomycete agents against three serious agricultural pests, Mythimna separata, Heterodera glycines, and Phytophthora capsici. Among all tested compounds: (i) compound 8p showed more significant insecticidal activity than toosendanin, and the final mortality rates of 8p and toosendanin against M. separata (1 mg mL-1) were 70.4%, and 51.9%, resp.; (ii) compound 7a exhibited more promising nematicidal activity than paeonol, and the median lethal concentration (LC50) values of 7a and 1 against H. glycines were 15.47 and 50.80 mg L-1, resp.; (iii) compounds 7n and 13m displayed more significant anti-oomycete activity compared to zoxamide against Phytophthora capsici, and the median effective concentration (EC50) values of 7n, 13m, and zoxamide were 23.72, 24.51, and 26.87 mg L-1, resp.; and the protective effect of the compounds against Phytophthora capsici in vivo further confirmed the effectiveness of the agents. This study suggested that the introduction of a nitro at the C5 or C3 position of paeonol could improve its bioactivity against M. separata, H. glycines, and Phytophthora capsici.
Pest Management Science published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C8H8O2, HPLC of Formula: 118-90-1.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia