Fedtke, M. published the artcileOxidative inhibitors. I. Ring-alkylated aromatic amines. Preparation of ring alkylated aniline derivatives, Category: catalysis-chemistry, the publication is Journal fuer Praktische Chemie (Leipzig) (1965), 29(3-6), 259-70, database is CAplus.
tert-Bu radical was introduced into aromatic amines by heating at 200-50¡ã with isobutylene in an autoclave at maximum 100 atm. using Al, AlCl3, or HgCl2 as catalyst. PhNH2 gave 41.3% p-tert-BuC6H4NH2 (b16 124¡ã, n20D 1.5373; acetate m. 171¡ã; benzoate m. 169-71¡ã) and 17% 2,4- and 2,6-(Me3C)2C6H3NH2. p-Toluidine gave 41% 2,4-Me(Me3C)C6H3NH2 (b1 85¡ã, n20D 1.5360; acetate m. 167%; benzoate m. 173¡ã). p-Toluidine gave 41.2% 4,2-Me(Me3C)C6H3NH2 (b1 81¡ã, n20D 1.5368; acetate m. 162-4¡ã) and 1.6% 4,2,6-Me(Me3C)2C6H2NH2 (b1 100-20¡ã, m. 128-9¡ã). Similarly ArNMe2 gave the following alkylated N,N-dimethylamines (alkyl, % yield, b.p. or m.p., and n20D given): p-tert-Bu, 29.3, b12 123¡ã, 1.5293; 2,6-Et2, 79.8, b3 90¡ã, 1.5095; 2,6-(iso-Pr2, 81.6, b2.5 86¡ã, 1.5002; 2,4-(tert-Bu)2, 35-9, m. 77-8¡ã, –; 4,2,6-MeEt2, 78.0, b3 92¡ã, 1.5084; 4,2,6-Me(iso-Pr)2, 59.1, m. 47.58.5,–.
Journal fuer Praktische Chemie (Leipzig) published new progress about 2909-77-5. 2909-77-5 belongs to catalysis-chemistry, auxiliary class Amine,Benzene, name is 2,6-Diisopropyl-N,N-dimethylaniline, and the molecular formula is C14H23N, Category: catalysis-chemistry.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia