Sun, Hao published the artcileApproach to Vicinal t-Boc-amino Dibromides via Catalytic Aminobromination of Nitrostyrenes without Using Chromatography and Recrystallization, Application In Synthesis of 4230-93-7, the publication is Journal of Organic Chemistry (2013), 78(3), 1171-1175, database is CAplus and MEDLINE.
In the presence of tripotassium phosphate trihydrate, tert-Bu N,N-dibromocarbamate (prepared from tert-Bu carbamate) added regioselectively to ¦Â-nitrostyrenes RCH:CHNO2 [R = Ph, 4-ClC6H4, 4-MeOC6H4, 2-ClC6H4, 4-MeC6H4, 4-F3CC6H4, 4-NCC6H4, 2-naphthyl, 1-naphthyl, 2-PhCH2OC6H4, 2,6-Cl2C6H3, 3,4-Cl2C6H3, 4-FC6H4, 4-BrC6H4, 3-FC6H4, 3-Br-4-MeOC6H3, 2-MeOC6H4, 3,4-(MeO)2C6H3, 4-Me3CC6H4] in 1,2-dichloroethane to give tert-Bu ¦Á-(dibromonitromethyl)benzylcarbamates RCH(NHBoc)C(NO2)Br2 [R = Ph, 4-ClC6H4, 4-MeOC6H4, 2-ClC6H4, 4-MeC6H4, 4-F3CC6H4, 4-NCC6H4, 2-naphthyl, 1-naphthyl, 2-PhCH2OC6H4, 2,6-Cl2C6H3, 3,4-Cl2C6H3, 4-FC6H4, 4-BrC6H4, 3-FC6H4, 3-Br-4-MeOC6H3, 2-MeOC6H4, 3,4-(MeO)2C6H3, 4-Me3CC6H4] in 82-99% yields. The solubility of the products allowed them to be isolated in pure form by extraction with hexanes rather than requiring chromatog. or recrystallization for purification
Journal of Organic Chemistry published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C15H14O, Application In Synthesis of 4230-93-7.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia