Zhou, Qianghui’s team published research in Journal of the American Chemical Society in 135 | CAS: 1395786-30-7

Journal of the American Chemical Society published new progress about 1395786-30-7. 1395786-30-7 belongs to catalysis-chemistry, auxiliary class Inhibitor, name is Dbco-maleimide, and the molecular formula is C38H24F4O4P2, COA of Formula: C25H21N3O4.

Zhou, Qianghui published the artcileBioconjugation by Native Chemical Tagging of C-H Bonds, COA of Formula: C25H21N3O4, the publication is Journal of the American Chemical Society (2013), 135(35), 12994-12997, database is CAplus and MEDLINE.

A general C-H functionalization method for the tagging of natural products and pharmaceuticals is described. An azide-containing sulfinate reagent allows the appendage of azidoalkyl chains onto heteroaromatics, the product of which can then be attached to a monoclonal antibody by a “click” reaction. This strategy expands the breadth of bioactive small mols. that can be linked to macromols. in a manner that is beyond the scope of existing methods in bioconjugation to permit tagging of the “seemingly untaggable”.

Journal of the American Chemical Society published new progress about 1395786-30-7. 1395786-30-7 belongs to catalysis-chemistry, auxiliary class Inhibitor, name is Dbco-maleimide, and the molecular formula is C38H24F4O4P2, COA of Formula: C25H21N3O4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia