Firestone, Raymond A. published the artcileSelective delivery of cytotoxic compounds to cells by the LDL pathway, HPLC of Formula: 30670-30-5, the publication is Journal of Medicinal Chemistry (1984), 27(8), 1037-43, database is CAplus and MEDLINE.
Cytotoxic compounds were prepared for reconstitution with LDL (low-d. lipoproteins) to be delivered to cancer cells that internalize LDL, and evaluated by measuring the toxicity of reconstituted LDL toward test cells, SV-589 (SV-40 transformed human fibroblasts) bearing LDL receptors. Selectivity was determined by comparison, either with mutant cells with few LDL receptors, or with reconstituted methylated LDL (not recognized by LDL receptors) or normal cells. N-[[[4-(3¦Â–(Oleoyloxy)androst-5-en-17¦Â-yl]pentyl]oxy]carbonyl]-N,N-bis(2-chloroethyl)amine (I) [90343-98-9] reconstituted well and was delivered exclusively via the LDL pathway in amounts capable of killing 100% cells.
Journal of Medicinal Chemistry published new progress about 30670-30-5. 30670-30-5 belongs to catalysis-chemistry, auxiliary class Polyfluoroalkanes, name is 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heptadecafluorodecan-1-amine, and the molecular formula is C10H6F17N, HPLC of Formula: 30670-30-5.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia