Crystal Growth & Design published new progress about 38260-01-4. 38260-01-4 belongs to catalysis-chemistry, auxiliary class Chelating Agents, name is N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, and the molecular formula is C6H20Cl2N4, Recommanded Product: N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride.
Henriet, Theo published the artcileTriethylenetetramine Dihydrochloride: Interactions and Conformations in Two Anhydrous Structures and a Hydrate, Recommanded Product: N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, the publication is Crystal Growth & Design (2015), 15(1), 348-357, database is CAplus.
Triethylenetetramine is a polyamine type chelating ligand for Cu(II), which is currently used, mainly in its dihydrochloride form, as an alternative to D-penicillamine against Wilson’s disease. Because knowledge about the solid-state behavior of pharmaceuticals is a prerequisite for the development of an effective dosage form, the crystal structures of two triethylenetetramine dihydrochloride polymorphs were determined, and the IR spectra and thermal expansion were studied. No suitable crystals could be obtained of the two anhydrous forms, for which the structures were solved from x-ray powder diffraction. Form I is monoclinic, space group P21/n with a 11.0475(4), b 4.87475(16), c 11.1178(4) ?, and ¦Â 106.9826(13)¡ã with Z = 2. Form II is also monoclinic, space group P21/c with a 10.6734(6), b 12.3613(6), c 9.8479(7) ?, and ¦Â 115.985(3)¡ã with Z = 4. A recurring structural element is a ionic interaction between two chloride ions and two ammonium groups each organized in a diamond pattern present in the dihydrate (the salt is hygroscopic) and anhydrous form I. The mol. conformations are different in both anhydrous forms and in the dihydrate. Comparison of the thermal expansions demonstrates that form I has the smallest thermal expansion and thus possesses the strongest intermol. interactions.
Crystal Growth & Design published new progress about 38260-01-4. 38260-01-4 belongs to catalysis-chemistry, auxiliary class Chelating Agents, name is N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, and the molecular formula is C6H20Cl2N4, Recommanded Product: N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia