Zhou, Ming published the artcileDesign, synthesis and biological evaluation of indeno[1,2-d]thiazole derivatives as potent histone deacetylase inhibitors, Product Details of C3H8N2S, the publication is Bioorganic & Medicinal Chemistry Letters (2013), 23(11), 3200-3203, database is CAplus and MEDLINE.
Novel indeno[1,2-d]thiazole hydroxamic acids were designed, synthesized, and evaluated for histone deacetylases (HDACs) inhibition and antiproliferative activities on tumor cell lines. Most of the tested compounds exhibited HDAC inhibition and antiproliferative activity against both MCF7 and HCT116 cells with GI50 values in the sub-micromolar range. Among them, compound I showed good inhibitory activity against pan-HDAC with IC50 value of 0.14 ¦ÌM and significant growth inhibition on MCF7 and HCT116 cells with GI50 values of 0.869 and 0.535 ¦ÌM, resp.
Bioorganic & Medicinal Chemistry Letters published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C12H9N3O4, Product Details of C3H8N2S.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia