Kohno, Hiroyuki published the artcileEffects of intracerebroventricular administration of aliphatic diamines on ingestive behavior in the rat, HPLC of Formula: 10517-44-9, the publication is Japanese Journal of Pharmacology (1981), 31(2), 211-20, database is CAplus and MEDLINE.
The pharmacol. effects of intracerebroventricularly administered aliphatic diamines on ingestive behavior were measured in male rats adapted to a 4 h/day feeding and drinking schedule. 1,2-Ethanediamine-2HCl (ETD) [333-18-6], 1,3-propanediamine-2HCl (PRD) [10517-44-9], putrescine (PUT) [110-60-1], cadaverine-2HCl (CAD) [1476-39-7], and 1,6-hexanediamine-2HCl (HED) [6055-52-3] suppressed feeding and drinking behavior in a dose-dependent manner, but not unless a relatively high dose (>80 ¦Ìg) was given. The approx. anorectic potency was HED > CAD ¡Ö PUT > ETD > PRD. A sedation was also produced in fairly good parallel to these alterations in feeding and drinking behavior. Thus, there appears to be a relation between the length of the C chain and the potency of the pharmacol. action.
Japanese Journal of Pharmacology published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, HPLC of Formula: 10517-44-9.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia