Shumaila, Abdullah M. A. published the artcileSynthesis of tetrahydro-5-azaindoles and 5-azaindoles using Pictet-Spengler reaction-appreciable difference in products using different acid catalysts, Recommanded Product: 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, the publication is Tetrahedron (2011), 67(5), 936-942, database is CAplus.
Pictet-Spengler condensation of 2-(aryl)-2-(1H-pyrrol-2-yl)ethanamines using conventional acid catalysts like TMSCl or TFA resulted in the formation of substituted 5-azaindoles involving a tandem one pot four step reaction sequence. By contrast, use of glacial acetic acid furnished the targeted tetrahydro-5-azaindoles in diastereoselective manner. These were readily dehydrogenated to 5-azaindoles.
Tetrahedron published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C5H11NO2S, Recommanded Product: 1,2-Dimethoxy-4-(2-nitrovinyl)benzene.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia