Suzuki, Toshio published the artcileA simple and convenient preparation of triethylene tetramine dihydrochloride (trien) for the treatment of Wilson’s disease and its stability, HPLC of Formula: 38260-01-4, the publication is Byoin Yakugaku (1987), 13(6), 335-9, database is CAplus.
Treatment of triethylene tetramine with anhydrous MeOH-HCl solution derived from AcCl and MeOH at 0¡ã, followed by recrystallization provided pure triethylene tetramine di-HCl (trien di-HCl). The compound is less hygroscopic than that prepared by the preceding procedure. Examination of its stability and drug activity under various conditions suggests than an aqueous solution of trien could also be useful for the treatment of Wilson’s disease.
Byoin Yakugaku published new progress about 38260-01-4. 38260-01-4 belongs to catalysis-chemistry, auxiliary class Chelating Agents, name is N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, and the molecular formula is C28H18O4, HPLC of Formula: 38260-01-4.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia