Winkelmann, E.’s team published research in Arzneimittel-Forschung in 26 | CAS: 1821-27-8

Arzneimittel-Forschung published new progress about 1821-27-8. 1821-27-8 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is Bis(4-nitrophenyl)amine, and the molecular formula is C14H10O4, Recommanded Product: Bis(4-nitrophenyl)amine.

Winkelmann, E. published the artcileChemotherapeutically active nitro compounds. Part 2: nitrodiphenyl sulfones, Recommanded Product: Bis(4-nitrophenyl)amine, the publication is Arzneimittel-Forschung (1976), 26(8), 1543-7, database is CAplus and MEDLINE.

The 58 4-nitro-4′-aminodiphenyl sulfones and related compounds tested had a spectrum of tuberculostatic and antimalarial activity similar to that of 4,4′-diaminodiphenyl sulfone (DDS) [80-08-0], but offered no significant advantages over DDS. The tested compounds were presumably reduced to DDS derivatives in vivo. For example, 4-nitro-4′-formamidodiphenyl sulfone (I) [6784-23-2] at 150 mg/kg orally was highly effective against Mycobacterium bovis and Plasmodium berghii infections in mice.

Arzneimittel-Forschung published new progress about 1821-27-8. 1821-27-8 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is Bis(4-nitrophenyl)amine, and the molecular formula is C14H10O4, Recommanded Product: Bis(4-nitrophenyl)amine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia