Balachandra, Biguvu published the artcileIodine catalyzed one-pot synthesis of highly substituted N-methyl pyrroles via [3 + 2] annulation and their in vitro evaluation as antibacterial agents, Safety of 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, the publication is RSC Advances (2015), 5(79), 64781-64789, database is CAplus.
A class of highly substituted pyrroles I [R = 2-F, 3-Cl, 4-OCH3, etc.] have been synthesized via a simple, fast, and efficient method using environmentally friendly iodine catalyzed [3 + 2] annulation. N-Methyl-N-[(E)-1-(methylsulfanyl)-2-nitro-1-ethenyl]amine (NMSM) and U+03B2-nitrostyrenes underwent cycloaddition to afford the desired products I in excellent yields under solvent and metal free conditions. All the pyrrole derivatives I were evaluated for their in vitro anti-bacterial activity. Among the synthesized pyrrole derivatives I [R = H, 3-OCH3, 3,4,5-(OCH3)3, 4-F, 4-Cl, 2-Br, 3-OH, 4-NO2, 1,2-C4H4] displayed good inhibitory properties against a panel of Gram pos. and neg. infectious pathogens.
RSC Advances published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H11NO4, Safety of 1,2-Dimethoxy-4-(2-nitrovinyl)benzene.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia