Kaur, Sandeep published the artcileConventional as well as microwave assisted synthesis and microbial effect of some new acrylamides, Related Products of catalysis-chemistry, the publication is Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (2013), 52B(12), 1513-1520, database is CAplus.
Knoevenagel condensation of a variety of aromatic aldehydes with acetic acid in the presence of sodium borohydride gave the corresponding cinnamic acids R1CH:CHCO2H (R1 = Ph, 2-ClC6H4, 4-ClC6H4, 3-O2NC6H4, 2-MeOC6H4, 4-MeOC6H4) which further reacted with furfurylamine or 2-aminopyridine either by conventional method in the presence of a catalytic amount of boric acid or using microwave irradiation to form the corresponding cinnamides R1CH:CHC(O)NHR2 (R2 = 2-furylmethyl, 2-pyridyl) (I). For all the compounds, the amidation under microwave irradiation conditions gave higher yields and took less time than the reactions under conventional heating conditions. The resulting amides were screened for their antimicrobial activity against bacteria [Bacillus sp. (BSY 101), Pseudomonas sp. (LK 791) and Ensifer sp. (IND 2)], fungus (Ascochyta blight) and yeast (Sacchromyces cerevisiae). The majority of the synthesized amides showed poor inhibition against Bacillus sp., Pseudomonas sp. and Ensifer sp. The compounds I (R1 = 4-ClC6H4, 4-MeOC6H4; R2 = 2-furylmethyl) and I (R1 = 2-ClC6H4, 4-MeOC6H4; R2 = 2-pyridyl) showed the best activity against Ensifer sp. The products containing a pyridine moiety were found to be more effective against bacteria than those based on furfurylamine. All the amides were ineffective against fungus and yeast.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 1772-76-5. 1772-76-5 belongs to catalysis-chemistry, auxiliary class Benzenes, name is (E)-3-(3-Nitrophenyl)acrylic acid, and the molecular formula is C9H7NO4, Related Products of catalysis-chemistry.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia