Kim, Jaeseung published the artcileSilanediol peptidomimetics. Evaluation of four diastereomeric ACE inhibitors, Formula: C12H10F2Si, the publication is Bioorganic & Medicinal Chemistry Letters (2004), 14(11), 2853-2856, database is CAplus and MEDLINE.
Four diastereomers, e.g., I [X = Si(OH)2], of a Phe-Ala peptide mimic incorporating a central silanediol group have been individually prepared and tested as inhibitors of angiotensin-converting enzyme (ACE). Three of the silanediols exhibit levels of inhibition that are similar to those of corresponding ketones reported by Almquist. For the fourth diastereomer, with both stereogenic carbons inverted relative to the most active isomer I, the ketone gives the least enzyme inhibition whereas the silanediol shows a surprisingly low IC50 value.
Bioorganic & Medicinal Chemistry Letters published new progress about 312-40-3. 312-40-3 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Difluorodiphenylsilane, and the molecular formula is C12H10F2Si, Formula: C12H10F2Si.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia