Matsufuji, Tetsuyoshi published the artcileDiscovery of novel chiral diazepines as bombesin receptor subtype-3 (BRS-3) agonists with low brain penetration, Formula: C15H14O3, the publication is Bioorganic & Medicinal Chemistry Letters (2014), 24(3), 750-755, database is CAplus and MEDLINE.
The discovery and optimization of a novel series of BRS-3 agonists are described. We explored a potent BRS-3 agonist with low brain penetration to avoid an adverse effect derived from central nervous system exposure. Through the derivatization process, chiral diazepines I (R1 = iso-Bu, 2-methylpyridin-5-yl) were identified as possessing low brain penetration as well as potent in vitro activity against human and mouse BRS-3s.
Bioorganic & Medicinal Chemistry Letters published new progress about 1860-58-8. 1860-58-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(3-(Benzyloxy)phenyl)acetic acid, and the molecular formula is C15H14O3, Formula: C15H14O3.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia