Pandeya, S. N. published the artcileSynthesis, anticonvulsant and analgesic activity of 1,2,4-dithiazoline derivatives, Recommanded Product: 1,1-Dimethylthiourea, the publication is Indian Journal of Pharmaceutical Sciences (1982), 44(2), 31-3, database is CAplus.
Iminodithiazolines I (R = 4-EtOC6H4NH, Me2N; R1 = Ph, 4-MeC6H4, PhCH2, Me) were prepared by S-benzylating RCSNH2, treating RC(:NH)SCH2Ph with R1NCS, and oxidative cyclization of R1NHCSN:CRSCH2Ph with Br2. I (R = 4-MeC6H4, R1 = CH2Ph) was obtained as a by-product. At 10 mg/kg i.p. I (R = 4-EtOC6H4NH, R1 = Ph, 4-MeC6H4; R = NMe2, R1 = 4-MeC6H4; R = 4-MeC6H4, R1 = CH2Ph) had 40-80% anticonvulsant activity in maximum electroshock test. I (R = 4-EtOC6H4NH, R1 = 4-MeC6H4, PhCH2; R = 4-MeC6H4, R1 = CH2Ph) had analgesic activity at 10 mg/kg i.p. in rats.
Indian Journal of Pharmaceutical Sciences published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Recommanded Product: 1,1-Dimethylthiourea.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia