Wong, Marie L. J. published the artcileDirect catalytic asymmetric synthesis of ¦Á-chiral bicyclo[1.1.1]pentanes, HPLC of Formula: 22693-41-0, the publication is Nature Communications (2021), 12(1), 1644, database is CAplus and MEDLINE.
An approach to synthesize ¦Á-chiral bicyclo[1.1.1]pentanes I (R = Me, Bn, thiophen-2-yl, etc.) (BCPs) involving the direct, asym. addition of simple aldehydes RCH2CHO to [1.1.1]propellane, the predominant BCP precursor was described. This is achieved by combining a photocatalyst and an organocatalyst to generate a chiral ¦Á-iminyl radical cation intermediate, which installs a stereocenter simultaneously with ring-opening of [1.1.1]propellane. The reaction proceeds under mild conditions, displays broad scope, and provides an array of ¦Á-chiral BCPs I in high yield and enantioselectivity. They also present a theor. model for stereoinduction in this mode of photoredox organocatalysis.
Nature Communications published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C8H7NO4, HPLC of Formula: 22693-41-0.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia