Athavan, Gayathri published the artcileDirect Evidence for Competitive C-H Activation by a Well-Defined Silver XPhos Complex in Palladium-Catalyzed C-H Functionalization, Application In Synthesis of 1206-46-8, the publication is Organometallics, database is CAplus.
Increasing evidence indicates that Ag salts can play a role in the C-H activation step of Pd-catalyzed C-H functionalization. Here the authors isolate a Ag(I) complex by C-H bond activation and demonstrate its catalytic competence for C-H functionalization. Ag carbonate, a common but highly insoluble additive, reacts with pentafluorobenzene in the presence of a bulky phosphine, XPhos, to form the C-H bond activation product Ag(C6F5)(XPhos). By isolating and fully characterizing this complex and the related carbonate and iodide complexes, [Ag(XPhos)]2(¦Ì-¦Ê2,¦Ê2-CO3) and [AgI(XPhos)]2, well-defined Ag(I) complexes can operate in conjunction with Pd complexes to achieve C-H functionalization even at ambient temperature Reactions are tested against the standard cross-coupling of C6F5H with 4-iodotoluene, catalyzed by Pd acetate at 60¡ã in the presence of Ag carbonate and Xphos. Key observations are that (a) PdIPh(XPhos) reacts stoichiometrically with Ag(C6F5)(XPhos) to form Ph-C6F5 instantly at room temperature; (b) catalytic cross coupling can be achieved using 5% Ag(C6F5)(XPhos) as the sole Ag source; and (c) Pd acetate (typical precatalyst) can be replaced for catalytic cross coupling by the expected oxidative addition compound PdIPh(XPhos). These studies lead to a catalytic cycle in which Ag(I) plays the C-H bond activation role and Pd plays the coupling role. Also, the phosphine can be exchanged between Ag complexes, ensuring that it is recycled even though Ag carbonate is consumed during catalytic cross-coupling.
Organometallics published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C9H9F5Si, Application In Synthesis of 1206-46-8.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia