Gu, Chengyihan published the artcileVisible-light-mediated amidation from carboxylic acids and tertiary amines via C-N cleavage, Quality Control of 118-90-1, the publication is Chemical Communications (Cambridge, United Kingdom) (2022), 58(39), 5873-5876, database is CAplus and MEDLINE.
Synthesis of tertiary amides RC(O)NR1R2 [R = Ph, 4-MeC6H4, 4-PhC6H4, etc.; R1 = R2 = Et, n-Pr; R1R2 = CH2(CH2)3CH2] via iridium photocatalyzed amidation of carboxylic acids and tertiary amines through C-N bond cleavage was reported. A wide scope of structurally diverse carboxylic acids participated smoothly in the reaction, providing the desired tertiary amides with moderate-to-good yields (up to 93% yield). This amidation strategy provided an alternative way to address the regioselectivity between nucleophilic functional groups, thus complementing the functional group compatibility of classical amidation protocols. Its synthetic robustness was also proved by the late-stage modification of several complex mols. and gram-scale applications.
Chemical Communications (Cambridge, United Kingdom) published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C8H8O2, Quality Control of 118-90-1.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia