Ke, Jie published the artcileCopper-Catalyzed Radical/Radical Csp3-H/P-H Cross-Coupling: ¦Á-Phosphorylation of Aryl Ketone O-Acetyloximes, Name: Dimesitylphosphine oxide, the publication is Angewandte Chemie, International Edition (2015), 54(22), 6604-6607, database is CAplus and MEDLINE.
The selective radical/radical cross-coupling of two different organic radicals is a great challenge due to the inherent activity of radicals. A Cu-catalyzed selective radical/radical Csp3-H/P-H cross-coupling was developed. This work offers a simple way toward ¦Â-ketophosphonates by oxidative coupling of aryl ketone o-acetyloximes with phosphine oxides using CuCl as catalyst and PCy3 as ligand in dioxane under N2 atmosphere at 130¡ã for 5 h with yields ranging from 47% to 86%. The preliminary mechanistic studies by EPR showed that, 1: the reduction of ketone o-acetyloximes generates iminium radicals, which could isomerize to ¦Á-sp3-C radical species; 2: P radicals were generated from the oxidation of phosphine oxides. Various aryl ketone o-acetyloximes and phosphine oxides were suitable for this transformation.
Angewandte Chemie, International Edition published new progress about 23897-16-7. 23897-16-7 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Dimesitylphosphine oxide, and the molecular formula is C18H23OP, Name: Dimesitylphosphine oxide.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia