Yao, Xiyuan’s team published research in Inorganic Chemistry in 58 | CAS: 1395786-30-7

Inorganic Chemistry published new progress about 1395786-30-7. 1395786-30-7 belongs to catalysis-chemistry, auxiliary class Inhibitor, name is Dbco-maleimide, and the molecular formula is C2H2N4O2, HPLC of Formula: 1395786-30-7.

Yao, Xiyuan published the artcileCysteine-Directed Bioconjugation of a Platinum(II)-Acridine Anticancer Agent, HPLC of Formula: 1395786-30-7, the publication is Inorganic Chemistry (2019), 58(1), 43-46, database is CAplus and MEDLINE.

Classical maleimide Michael addition chem. in conjunction with copper-free click chem. was investigated as a synthetic strategy to attach cytotoxic platinum-acridine hybrid agents to carrier proteins. The structural integrity and selectivity of the model payloads, which were validated in human serum albumin (HSA) using mass spectrometric anal. and heteronuclear 2D 1H-15N HSQC NMR experiments, may have broad utility for the targeted delivery of highly cytotoxic platinum acridines and other nonclassical platinum containing anticancer agents.

Inorganic Chemistry published new progress about 1395786-30-7. 1395786-30-7 belongs to catalysis-chemistry, auxiliary class Inhibitor, name is Dbco-maleimide, and the molecular formula is C2H2N4O2, HPLC of Formula: 1395786-30-7.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia