Asano, Michizo published the artcileThe fate of branched-chain fatty acids in the animal body. I. A contribution to the problem of Hildebrandt acid, Recommanded Product: 2-Butylhexanoic acid, the publication is Yakugaku Zasshi (1948), 147-9, database is CAplus.
cf. C.A. 44, 2626g; following abstract From rabbits administered with branched-chain fatty acids 48 hrs.’ urine was collected. 8.5 g. of l-rhodinic acid (b9 = 139-140¡ã, [¦Á]15D = -6.44¡ã, n26D = 1.4578) resulted in excretion of 3.45 g. of an acid (I), b0.2 = 174-186¡ã, m.p. = 102-103.5¡ã, (from water), [¦Á]D = -13.5¡ã, and 45.05% of COOH calculated for C10H16O4. From 10 g. of administered d-citronellic acid (b11 = 141-3¡ã, [¦Á]D = +6.31¡ã) there was obtained 6.07 g. of a viscous liquid (II), b1.2 = 165-190¡ã, m.p. = 103-4¡ã [¦Á]D = +15.6¡ã, and 45.03% of COOH calculated for C10H16O4. From 11 g. of d-citronellal (b17 = 97¡ã, [¦Á]D = -3.64¡ã, n13D = 1.4518), 2.33 g. of an acid (III) was isolated, showing b0.05 = 160-180¡ã, m.p. = 103-4¡ã, and [¦Á]D = +15.3¡ã. From 22 g. of geraniol (b17 = 120-2¡ã, n13D = 1.4755, [¦Á]D = -2.89¡ã), 5 g. of a viscous liquid (IV), b1.5 = 170-95¡ã, was obtained, and further fractionated into two parts: water-insoluble part (V), crystallized from alc., which showed m.p. = 190-1¡ã; water-insoluble part, m.p. = 102-4¡ã, [¦Á]D = +14.1¡ã, and 44.89% of COOH calculated for C10H16O4. By mixed m.p. determinations, it was proved that V was Hildebrandt acid, while II, III, and IV were identical with dihydro-Hildebrandt acid, and I corresponded to the latter’s optical antipode.
Yakugaku Zasshi published new progress about 3115-28-4. 3115-28-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is 2-Butylhexanoic acid, and the molecular formula is C10H20O2, Recommanded Product: 2-Butylhexanoic acid.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia