Casy, A. F. published the artcileCarbon-13 NMR as a convenient aid to the differentiation of triethylenetetraamine (TETA) dihydrochloride from related impurities, Recommanded Product: N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, the publication is Journal of Pharmacy and Pharmacology (1981), 33(5), 333-4, database is CAplus and MEDLINE.
Proton-noise and off-resonance decoupled 13C spectra were obtained on an NMR spectrometer for recrystallized TETA-2HCl [38260-01-4] in D2O. The correct number of lines required by the 3 nonequivalent C atoms in this structure were displayed, whereas that of the impurity, tris(2-aminoethyl)amine-3HCl [4097-89-6] showed one less signal, consistent with 2 nonequivalent C atoms. A com. sample of diethylenetriamine [111-40-0] had a spectrum with 2 major lines only. Piperazine and other impurities were observable in spectrums of TETA base samples. Levels of impurities of 5% and probably lower could be detected.
Journal of Pharmacy and Pharmacology published new progress about 38260-01-4. 38260-01-4 belongs to catalysis-chemistry, auxiliary class Chelating Agents, name is N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, and the molecular formula is C6H20Cl2N4, Recommanded Product: N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia