Lin, Nai-Pin published the artcileSynthesis and characterization of phenylboronic acid-modified insulin with glucose-dependent solubility, Application In Synthesis of 71989-31-6, the publication is Frontiers in Chemistry (Lausanne, Switzerland) (2022), 859133, database is CAplus and MEDLINE.
Glucose-responsive insulin represents a promising approach to regulate blood glucose levels. We previously showed that attaching two fluorophenylboronic acid (FPBA) residues to the C-terminal B chain of insulin glargine led to glucose-dependent solubility Herein, we demonstrated that relocating FPBA from B chain to A chain increased the baseline solubility without affecting its potency. Furthermore, increasing the number of FPBA groups led to increased glucose-dependent solubility
Frontiers in Chemistry (Lausanne, Switzerland) published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, Application In Synthesis of 71989-31-6.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia