Yuan, Kedong published the artcileArylation of gem-difluoroalkenes using a Pd/Cu Co-catalytic system that avoids ¦Â-fluoride elimination, Product Details of C14H14, the publication is Chemical Science (2021), 12(4), 1363-1367, database is CAplus and MEDLINE.
PdII/CuI co-catalyze an arylation reaction of gem-difluoroalkenes using arylsulfonyl chlorides to deliver ¦Á,¦Á-difluorobenzyl products. The reaction proceeded through a ¦Â,¦Â-difluoroalkyl-Pd intermediate that typically underwent unimol. ¦Â-F elimination to deliver monofluorinated alkene products in a net C-F functionalization reaction. However to avoid ¦Â-F elimination, the ¦Â,¦Â-difluoroalkyl-Pd intermediate were offered, an alternate low-energy route involving ¦Â-H elimination to ultimately deliver difluorinated products in a net arylation/isomerization sequence. Overall, this reaction enabled exploration of new reactivities of unstable fluorinated alkyl-metal species, while also providing new opportunities for transforming readily available fluorinated alkenes into more elaborate substructures.
Chemical Science published new progress about 613-33-2. 613-33-2 belongs to catalysis-chemistry, auxiliary class Benzene, name is 4,4′-Dimethyldiphenyl, and the molecular formula is C8H10S, Product Details of C14H14.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia