Brugarolas, P. published the artcileSynthesis of meta-substituted [18F]3-fluoro-4-aminopyridine via direct radiofluorination of pyridine N-oxides, Recommanded Product: Tetrabutylammonium hydrogencarbonate, the publication is Chemical Communications (Cambridge, United Kingdom) (2016), 52(44), 7150-7152, database is CAplus and MEDLINE.
A methodol. for the preparation of 3-fluoro-4-aminopyridine was developed via two-step procedure involving fluorination of 3-bromo-4-nitropyridine N-oxide to yield 3-fluoro-4-nitropyridine N-oxide as an intermediate in first step and its reduction via catalytic hydrogenation in second step. Furthermore, this approach was successfully applied for the preparation of [18F]3-fluoro-4-aminopyridine. The use of pyridine N-oxides for the preparation of fluoropyridines was unprecedented in chem. literature and had potential to offer a new way for the synthesis of these important structures in pharmaceuticals and radiopharmaceuticals.
Chemical Communications (Cambridge, United Kingdom) published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, Recommanded Product: Tetrabutylammonium hydrogencarbonate.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia