Ismail, Rehana published the artcileCationic imidazolium polymer monoliths for efficient solvent exchange, activation and fluorination on a continuous flow system, Application of Tetraethylammonium hydrogencarbonate, the publication is RSC Advances (2014), 4(48), 25348-25356, database is CAplus.
Polystyrene-imidazolium (PS-Im+Cl-) monolith was synthesized within a flow-through microfluidic chip and Teflon tubing for activating [18F]fluoride ions. The [18F]fluoride ions were trapped on the PS-Im+ monolith and were subsequently released with various phase-transfer catalysts (PTC) and carbonate or bicarbonate bases in microliter volumes of organic solvents containing 0.5% of water. The activated [18F]fluoride complex released from the PS-Im+ monolith was used to fluorinate various known PET probe precursors with diverse reactivity in a subsequent flow-through microfluidic chip without performing addnl. azeotropic distillation The fluorination yields under the optimized condition for the protected [18F]FDG, protected [18F]FLT, 4-[18F]fluoroethylbenzoate, and [18F]fallypride were 93%, 96%, 77% and 73%, resp. This method, utilizing the PS-Im+ monolith on a flow through microfluidic platform, enables the entire fluorine-18 radiochem. to be performed on a flow-through microfluidic device within a shorter synthesis time and with fluorination efficiency that is comparable to or higher than conventional means.
RSC Advances published new progress about 17351-61-0. 17351-61-0 belongs to catalysis-chemistry, auxiliary class Phase Transfer Catalyst, name is Tetraethylammonium hydrogencarbonate, and the molecular formula is C9H21NO3, Application of Tetraethylammonium hydrogencarbonate.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia