Zhao, Feng published the artcileDeoxygenative alkylation of tertiary amides using alkyl iodides under visible light, Application In Synthesis of 2051-95-8, the publication is Science China: Chemistry, database is CAplus.
A deoxygenative alkylation strategy was demonstrated and combined amides R1C(O)N(R2)R3 (R1 = 2-phenylethyl, 3-(naphthalen-2-yl)propyl, 2-(adamantan-1-yl)ethyl, etc.; R2 = Bn, Me, 2-(thiophen-2-yl)ethyl, etc.; R3 = Bn, Me, n-Pr, etc.) and alkyl iodides R4I (R4 = i-Pr, cyclopentyl, t-Bu, etc.) to build structurally diverse tertiary alkylamines R1CH(R4)NR(2)R3in a single step. Compared with previous deoxygenative alkylation of amides using organometallic reagents as functional partner, this work uses stable and easily available alkyl halides as functionalization reagents. The versatile and flexible strategy plus structural and functional diversity of readily available amides and alkyl iodides renders it highly appealing for the streamlined synthesis of tertiary amines and would be of much interest in areas such as pharmaceutical and agrochem. research.
Science China: Chemistry published new progress about 2051-95-8. 2051-95-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ketone, name is 3-Benzoylpropionicacid, and the molecular formula is C13H10F2, Application In Synthesis of 2051-95-8.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia